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  1. This article has been retracted. Please see the Retraction Notice for more detail: https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s12868-021-00644-1

    Authors: Sabine Wislet-Gendebien, Naomi P. Visanji, Shawn N. Whitehead, Diana Marsilio, Weimin Hou, Daniel Figeys, Paul E. Fraser, Steffany A. L. Bennett and Anurag Tandon
    Citation: BMC Neuroscience 2021 22:40
    Content type: Retraction Note Published on:

    The original article was published in BMC Neuroscience 2008 9:92

  2. Matrix metallopeptidase 9 (MMP9) has been implicated in a variety of neurological disorders, including Alzheimer’s disease (AD), where MMP9 levels are elevated in the brain and cerebrovasculature. Previously o...

    Authors: Charis Ringland, Jonas Elias Schweig, Maxwell Eisenbaum, Daniel Paris, Ghania Ait-Ghezala, Michael Mullan, Fiona Crawford, Laila Abdullah and Corbin Bachmeier
    Citation: BMC Neuroscience 2021 22:39
    Content type: Research Published on:

  3. The receptor for advanced glycation end-products (RAGE) is involved in neuroinflammation. This study investigated the changes in RAGE expression following noise-induced hearing loss.

    Authors: Chang Ho Lee, Kyung Woon Kim, Da-hye Lee, So Min Lee and So Young Kim
    Citation: BMC Neuroscience 2021 22:38
    Content type: Research article Published on:

  4. Pathophysiological evidence from temporal lobe epilepsy models highlights the hippocampus as the most affected structure due to its high degree of neuroplasticity and control of the dynamics of limbic structur...

    Authors: Miguel A. Núñez-Ochoa, Gustavo A. Chiprés-Tinajero, Nadia P. González-Domínguez and Laura Medina-Ceja
    Citation: BMC Neuroscience 2021 22:37
    Content type: Research article Published on:

  5. The neural networks underpinning language control and domain-general executive functions overlap in bilinguals, but existing evidence is mainly correlative. Here, we present the first neurofunctional evidence ...

    Authors: Yan Jing Wu, Mo Chen, Guillaume Thierry, Yongben Fu, Junjie Wu and Taomei Guo
    Citation: BMC Neuroscience 2021 22:36
    Content type: Research article Published on:

  6. Asymptomatic Moyamoya disease (MMD) impairs hemodynamic and cognitive function. The relationship between these changes, cerebral blood flow (CBF), and network connectivity remains largely unknown. The aim of t...

    Authors: Shihao He, Ziqi Liu, Yanchang Wei, Ran Duan, Zongsheng Xu, Cai Zhang, Li Yuan, Tian Li, Ning Ma, Xin Lou, Xiaoyuan Liu and Rong Wang
    Citation: BMC Neuroscience 2021 22:35
    Content type: Research Published on:

  7. The Grooved Pegboard Test (GPT) is widely adopted to evaluate manual dexterity, it presents normative data but the test is influenced by different factors. The influence of time spent on smartphones has not be...

    Authors: Luca Petrigna, Milda Treigienė, Ewan Thomas, Diba Mani, Simona Pajaujiene, Patrik Drid, Gioacchino Lavanco, Antonio Palma and Antonino Bianco
    Citation: BMC Neuroscience 2021 22:34
    Content type: Research article Published on:

  9. Autism spectrum disorder (ASD) is characterized by the core symptoms of impaired social interactions. Increasing evidence suggests that ASD has a strong genetic link with mutations in chromodomain helicase DNA...

    Authors: Stanislav M. Cherepanov, Maria Gerasimenko, Teruko Yuhi, Kazumi Furuhara, Chiharu Tsuji, Shigeru Yokoyama, Keiichi I. Nakayama, Masaaki Nishiyama and Haruhiro Higashida
    Citation: BMC Neuroscience 2021 22:32
    Content type: Research article Published on:

  10. Protective ventilation with lower tidal volumes reduces systemic and organ-specific inflammation. In sepsis-induced encephalopathy or acute brain injury the use of protective ventilation has not been widely in...

    Authors: Axel Nyberg, Erik Gremo, Jonas Blixt, Jesper Sperber, Anders Larsson, Miklós Lipcsey, Andreas Pikwer and Markus Castegren
    Citation: BMC Neuroscience 2021 22:31
    Content type: Research article Published on:

  11. In everyday life, negative emotions can be implicitly regulated by positive stimuli, without any conscious cognitive engagement; however, the effects of such implicit regulation on mood and related neuro-mecha...

    Authors: M. Berthold-Losleben, S. Papalini, U. Habel, K. Losleben, F. Schneider, K. Amunts and N. Kohn
    Citation: BMC Neuroscience 2021 22:30
    Content type: Research Published on:

  12. The implication of the steroids estradiol, progesterone and testosterone in cerebral vasospasm after aneurysmal subarachnoid hemorrhage (aSAH) has not been comprehensively assessed. In rodents, studies suggest...

    Authors: Jan Martin, Eva Plank, Bernhard Ulm, Jens Gempt, Maria Wostrack, Bettina Jungwirth and Simone M. Kagerbauer
    Citation: BMC Neuroscience 2021 22:29
    Content type: Research article Published on:

  13. Brain radiation exposure, in particular, radiotherapy, can induce cognitive impairment in patients, with significant effects persisting for the rest of their life. However, the main mechanisms leading to this ...

    Authors: Bo Xu Ren, Isaac Huen, Zi Jun Wu, Hong Wang, Meng Yun Duan, Ilonka Guenther, K. N. Bhanu Prakash and Feng Ru Tang
    Citation: BMC Neuroscience 2021 22:28
    Content type: Research article Published on:

  14. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Mara A. Guzmán-Ruiz, Amor Herrera-González, Adriana Jiménez, Alan Candelas-Juárez, Crystal Quiroga-Lozano, Claudia Castillo-Díaz, Erika Orta-Salazar, Diana Organista-Juárez, Sofía Díaz-Cintra and Rosalinda Guevara-Guzmán
    Citation: BMC Neuroscience 2021 22:27
    Content type: Correction Published on:

    The original article was published in BMC Neuroscience 2021 22:14

  16. Nociceptin/orphanin FQ (N/OFQ) has been revealed to play bidirectional roles in orofacial pain modulation. Calcitonin gene-related peptide (CGRP) is a well-known pro-nociceptive molecule that participates in t...

    Authors: Xinyu Yan, Han Han, Shizhen Zhang, Yanzhu Lu, Linghuan Ren, Yufei Tang, Xiaolong Li, Fan Jian, Yan Wang, Hu Long and Wenli Lai
    Citation: BMC Neuroscience 2021 22:25
    Content type: Research article Published on:

  17. Methamphetamine (METH) is one of the most widely abused illicit substances worldwide; unfortunately, its addiction mechanism remains unclear. Based on accumulating evidence, changes in gene expression and chro...

    Authors: Hui Li, Jing-An Chen, Qian-Zhi Ding, Guan-Yi Lu, Ning Wu, Rui-Bin Su, Fei Li and Jin Li
    Citation: BMC Neuroscience 2021 22:24
    Content type: Research article Published on:

  18. Tau theory explains how both intrinsically and perceptually guided movements are controlled by the brain. According to general tau theory, voluntary, self-paced human movements are controlled by coupling the t...

    Authors: Mehrdad Bahadori, Paola Cesari, Cathy Craig and Mehran Emadi Andani
    Citation: BMC Neuroscience 2021 22:23
    Content type: Research article Published on:

  19. Differences of genotypes between male and female have been studied in Parkinson’s disease (PD), but limited research has focused on the comparison between sexes with LRRK2 G2385 variant.

    Authors: Shi-Shuang Cui, Rao Fu, Juan-Juan Du, Yi-Qi Lin, Pei Huang, Chao Gao, Hai-Yan Zhou and Sheng-Di Chen
    Citation: BMC Neuroscience 2021 22:22
    Content type: Research article Published on:

  20. Hepatic encephalopathy (HE) is a neurological complication resulting from acute or chronic liver disease. Hyperammonemia leading to astrocyte swelling and cerebral edema in combination with neuroinflammation i...

    Authors: Fatme Seval Ismail, Timo Jendrik Faustmann, Franco Corvace, Anamariya Tsvetanova, Zahra Moinfar and Pedro M. Faustmann
    Citation: BMC Neuroscience 2021 22:21
    Content type: Research article Published on:

  21. Atherosclerotic plaques are often present in regions of arteries with complicated flow patterns. Vascular morphology plays important role in hemodynamics. In this study, we investigated the relationship betwee...

    Authors: Jinmei Zheng, Bin Sun, Ruolan Lin, Yongqi Teng, Xihai Zhao and Yunjing Xue
    Citation: BMC Neuroscience 2021 22:20
    Content type: Research article Published on:

  23. The SCN11A gene, encoded Nav1.9 TTX resistant sodium channels, is a main effector in peripheral inflammation related pain in nociceptive neurons. The role of SCN11A gene in the auditory system has not been well c...

    Authors: Mian Zu, Wei-Wei Guo, Tao Cong, Fei Ji, Shi-Li Zhang, Yue Zhang, Xin Song, Wei Sun, David Z. Z. He, Wei-Guo Shi and Shi-Ming Yang
    Citation: BMC Neuroscience 2021 22:18
    Content type: Research article Published on:

  24. Several studies have shown that glutamate neurotransmission in the nucleus accumbens (NAc) is required for the development of morphine-induced conditional place preference (CPP). In addition, metabotropic glut...

    Authors: Zahra Ebrahimi, Nazanin Kahvandi, Alireza Komaki, Seyed Asaad Karimi, Marzieh Naderishahab and Abdolrahman Sarihi
    Citation: BMC Neuroscience 2021 22:17
    Content type: Research article Published on:

  25. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Laszlo Szpisjak, Gabor Szaraz, Andras Salamon, Viola L. Nemeth, Noemi Szepfalusi, Gabor Veres, Balint Kincses, Zoltan Maroti, Tibor Kalmar, Malgorzata Rydzanicz, Rafal Ploski, Peter Klivenyi and Denes Zadori
    Citation: BMC Neuroscience 2021 22:16
    Content type: Correction Published on:

    The original article was published in BMC Neuroscience 2021 22:7

  26. Rupture of intracranial aneurysm (IA) is the main cause of devastating subarachnoid hemorrhage, which urges our understanding of the pathogenesis and regulatory mechanisms of IA. However, the regulatory roles ...

    Authors: Yuan-Bo Pan, Jianan Lu, Biao Yang, Cameron Lenahan, Jianmin Zhang and Anwen Shao
    Citation: BMC Neuroscience 2021 22:15
    Content type: Research article Published on:

  27. Alzheimer’s disease (AD) is characterized by cognitive impairment that eventually develops into dementia. Amyloid-beta (Aβ) accumulation is a widely described hallmark in AD, and has been reported to cause olf...

    Authors: Mara A. Guzmán-Ruiz, Amor Herrera-González, Adriana Jiménez, Alan Candelas-Juárez, Crystal Quiroga-Lozano, Claudia Castillo-Díaz, Erika Orta-Salazar, Diana Organista-Juárez, Sofía Díaz-Cintra and Rosalinda Guevara-Guzmán
    Citation: BMC Neuroscience 2021 22:14
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Neuroscience 2023 24:47

    The Correction to this article has been published in BMC Neuroscience 2021 22:27

  28. Aside from the homeostatic and circadian components, light has itself an important, direct as well as indirect role in sleep regulation. Light exerts indirect sleep effect by modulating the circadian rhythms. ...

    Authors: Örs Szalontai, Attila Tóth, Máté Pethő, Dóra Keserű, Tünde Hajnik and László Détári
    Citation: BMC Neuroscience 2021 22:13
    Content type: Research article Published on:

  29. Men and women show differences in sensitivity to reward and punishment, which may impact behavior in health and disease. However, the neural bases of these sex differences remain under-investigated. Here, by c...

    Authors: Isha Dhingra, Sheng Zhang, Simon Zhornitsky, Wuyi Wang, Thang M. Le and Chiang-Shan R. Li
    Citation: BMC Neuroscience 2021 22:12
    Content type: Research article Published on:

  30. Attachment theory demonstrates that early attachment experience shapes internal working models with mental representations of self and close relationships, which affects personality traits and interpersonal re...

    Authors: Min Deng, Xing Zhang, Xiaoyan Bi and Chunhai Gao
    Citation: BMC Neuroscience 2021 22:11
    Content type: Research article Published on:

  31. There is growing evidence for a positive correlation between measures of muscular strength and cognitive abilities. However, the neurophysiological correlates of this relationship are not well understood so fa...

    Authors: Fabian Herold, Tom Behrendt, Alexander Törpel, Dennis Hamacher, Notger G. Müller and Lutz Schega
    Citation: BMC Neuroscience 2021 22:10
    Content type: Research article Published on:

  32. We previously reported that heat shock protein 27 (HSP27) phosphorylation plays an important role in the activation of glucose-6-phosphate dehydrogenase (G6PD), resulting in the upregulation of the pentose pho...

    Authors: Kazuya Matsuo, Kohkichi Hosoda, Jun Tanaka, Yusuke Yamamoto, Taichiro Imahori, Tomoaki Nakai, Yasuhiro Irino, Masakazu Shinohara, Takashi Sasayama and Eiji Kohmura
    Citation: BMC Neuroscience 2021 22:9
    Content type: Research article Published on:

  33. It has been shown that eosinophils are decreased and monocytes are elevated in patients with acute ischemic stroke (AIS), but the impact of eosinophil-to-monocyte ratio (EMR) on clinical outcomes among AIS pat...

    Authors: Shuhong Yu, Yi Luo, Tan Zhang, Chenrong Huang, Yu Fu, Qiang Zhang, Fangyue Zeng, Hao Huang, Chunyuan Zhang and Zhiliang Guo
    Citation: BMC Neuroscience 2021 22:8
    Content type: Research article Published on:

  34. SYNE1 ataxia is an autosomal recessive hereditary condition, the main characteristic features of which are gait and limb ataxia and cerebellar dysarthria. Reports have revealed that the clinical phenotype of SYNE...

    Authors: Laszlo Szpisjak, Gabor Szaraz, Andras Salamon, Viola L. Nemeth, Noemi Szepfalusi, Gabor Veres, Balint Kincses, Zoltan Maroti, Tibor Kalmar, Malgorzata Rydzanicz, Rafal Ploski, Peter Klivenyi and Denes Zadori
    Citation: BMC Neuroscience 2021 22:7
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Neuroscience 2021 22:16

  35. Neuropathic pain (NeuP) is a complex, debilitating condition of the somatosensory system, where dysregulation between pro- and anti-inflammatory cytokines and chemokines are believed to play a pivotal role. As...

    Authors: Mika Jönsson, Björn Gerdle, Bijar Ghafouri and Emmanuel Bäckryd
    Citation: BMC Neuroscience 2021 22:6
    Content type: Research article Published on:

  36. The Period Circadian Regulator 2 (Per2) gene is important for the modulation of circadian rhythms that influence biological processes. Circadian control of the hypothalamus-pituitary-adrenal (HPA) axis is critica...

    Authors: Ashley L. Russell, Lauren Miller, Hannah Yi, Rita Keil, Robert J. Handa and T. John Wu
    Citation: BMC Neuroscience 2021 22:5
    Content type: Research article Published on:

  37. Astrocytes are responsible for a broad range of functions that maintain homeostasis in the brain. However, their response to the pro-inflammatory cytokines released by activated microglia in various neurologic...

    Authors: Emilia Zgórzyńska, Dawid Stulczewski, Barbara Dziedzic, Kuan-Pin Su and Anna Walczewska
    Citation: BMC Neuroscience 2021 22:4
    Content type: Research article Published on:

  39. Status epilepticus (SE) is a life-threatening neurological disorder. The hippocampus, as an important area of the brain that regulates cognitive function, is usually damaged after SE, and cognitive deficits of...

    Authors: Xin-Ming Luo, Jing Zhao, Wen-Yue Wu, Jie Fu, Zheng-Yu Li, Ming Zhang and Jie Lu
    Citation: BMC Neuroscience 2021 22:2
    Content type: Research article Published on:

  40. A common problem in neurophysiological signal processing is the extraction of meaningful information from high dimension, low sample size data (HDLSS). We present RoLDSIS (regression on low-dimension spanned i...

    Authors: Adrielle C. Santana, Adriano V. Barbosa, Hani C. Yehia and Rafael Laboissière
    Citation: BMC Neuroscience 2021 22:1
    Content type: Methodology article Published on:

  42. Conditioned pain modulation (CPM) evaluates the effect of a painful conditioning stimulus (CS) on a painful test stimulus (TS). Using painful cutaneous electrical stimulation (PCES) as TS and painful cold wate...

    Authors: A. T. L. Do, E. K. Enax-Krumova, Ö. Özgül, L. B. Eitner, S. Heba, M. Tegenthoff, C. Maier and O. Höffken
    Citation: BMC Neuroscience 2020 21:53
    Content type: Research article Published on:

  44. Ventromedial hypothalamic nucleus (VMN) gluco-regulatory transmission is subject to sex-specific control by estradiol. The VMN is characterized by high levels of aromatase expression.

    Authors: Md. Main Uddin, Mostafa M. H. Ibrahim and Karen P. Briski
    Citation: BMC Neuroscience 2020 21:51
    Content type: Research article Published on:

  45. Transcription factor 4 (TCF4) has been linked to human neurodevelopmental disorders such as intellectual disability, Pitt-Hopkins Syndrome (PTHS), autism, and schizophrenia. Recent work demonstrated that TCF4 par...

    Authors: Katharina Braun, Benjamin M. Häberle, Marie-Theres Wittmann and D. Chichung Lie
    Citation: BMC Neuroscience 2020 21:50
    Content type: Research article Published on:

  46. Previous studies have demonstrated that individuals with autism spectrum disorder (ASD) exhibit dysfunction in the three attention systems (i.e., alerting, orienting, and executive control) as well as atypical re...

    Authors: Sayaka Yoshimura, Kei Kobayashi, Tsukasa Ueno, Takashi Miyagi, Naoya Oishi, Toshiya Murai and Hironobu Fujiwara
    Citation: BMC Neuroscience 2020 21:49
    Content type: Research article Published on:

  47. To identify mechanisms of cortical plasticity of the visual cortex and to quantify their significance, sensitive parameters are warranted. In this context, multifocal visual evoked potentials (mfVEPs) can make...

    Authors: Robert Kolbe, Aykut Aytulun, Ann-Kristin Müller, Marius Ringelstein, Orhan Aktas, Alfons Schnitzler, Hans-Peter Hartung, Stefan Jun Groiss and Philipp Albrecht
    Citation: BMC Neuroscience 2020 21:48
    Content type: Research article Published on:

  48. We present first-time evidence for the immediate neural and behavioral effects of bifocal emotional processing via visualized tapping for two different types of negative emotions (fear and disgust) in a sample...

    Authors: Dina Wittfoth, Antonia Pfeiffer, Michael Bohne, Heinrich Lanfermann and Matthias Wittfoth
    Citation: BMC Neuroscience 2020 21:47
    Content type: Research article Published on:

  49. As a noninvasive perfusion-weighted MRI technique, arterial spin-labeling (ASL) was becoming increasingly used to evaluate cerebral hemodynamics in many studies. The relation between ASL-MRI and crossed cerebe...

    Authors: Juan Wang, Li-Jun Pan, Bin Zhou, Jin-Yan Zu, Yi-Xu Zhao, Yang Li, Wan-Qiu Zhu, Lei Li, Jian-Rong Xu and Zeng-Ai Chen
    Citation: BMC Neuroscience 2020 21:46
    Content type: Research article Published on:
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