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Fig. 6 | BMC Neuroscience

Fig. 6

From: Ventromedial hypothalamic nucleus neuronal nitric oxide knockdown effects on GABAergic neuron metabolic sensor and transmitter marker gene expression in the male rat

Fig. 6

Effects of VMN nNOS siRNA Pretreatment on Eu- and Hypoglycemic Patterns of 5’-AMP-Activated Protein Kinase-Alpha1 (AMPKα1) and AMPKα2 Gene Expression in VMNdm versus VMNvl GABAergic Neurons. Plots depict normalized AMPKα1 [Fig. 6A (VMNdm) and 6B (VMNvl)] or AMPKα2 [Fig. 6C (VMNdm) and 6D (VMNvl)] mRNA measures for GABA neurons collected from SCR siRNA/sc V (blue box-and-whisker plots, n = 12), nNOS siRNA/sc V (yellow box-and-whisker plots; n = 12), SCR siRNA/ sc INS (green box-and-whisker plots; n = 12), or nNOS siRNA/sc INS (orange box-and-whisker plots; n = 12) treatment groups. Statistical differences between discrete pairs of treatment groups are indicated by the following symbols: *p < 0.05; **p < 0.01; ***p < 0.001

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