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Fig. 7 | BMC Neuroscience

Fig. 7

From: Platelet-rich fibrin and silver nano-particles loaded chitosan treatment for post- laminectomy epidural scar adhesions: in vivo rats study model

Fig. 7

The histopathological and quantitative PCR evaluation of the effect of laminectomy and studied treatment PRF, Chi/Ag-NPs group, and combined PRF and Chi/Ag-NPs (PRF +) on the fibrosis and inflammation of the rats’ vertebral sections. The grades of epidural scar adhesion (A), arachnoid involvement (B), scaring tissue density (C), dural thickness (D), inflammation scoring (E), TGF-β1 and IL-6 (F, G) coding genes expression showed that laminectomy induced fibrosis and inflammation, while the applied treatment modalities significantly improved laminectomy induced inflammation and fibrosis. Significance was evaluated by One way ANOVA test with posttest Tucky’s multiple comparison test. * means P-value < 0.05, **means P-value < 0.001, while *** means P-value < 0.0001

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BMC Neuroscience

ISSN: 1471-2202

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