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Fig. 4 | BMC Neuroscience

Fig. 4

From: Platelet-rich fibrin and silver nano-particles loaded chitosan treatment for post- laminectomy epidural scar adhesions: in vivo rats study model

Fig. 4

Microscopic pictures showing normal structures of Pia mater (dashed black arrow); Dura mater (black arrow); B: Bone; S: spinal cord in control normal group (A). Excessive epidural deposition of scar tissue (blue arrow), massive Inflammation (thick black arrow), granuloma formation (yellow arrow) and dystrophic calcification (*) are seen around spinal cord leading to increased thickness of dura mater and marked adhesion with Pia mater in laminectomy group (grade 3 epidural fibrosis) (B–D). Moderate inflammation and epidural scar tissue formation (blue arrow) are seen in group PRF group (E). Milder inflammation and more epidural scar tissue formation (blue arrow) is seen in Chi/Ag-NPs group leading to focal adhesion of Pia to Dura mater (F). Very mild epidural fibrosis (blue arrow) is seen in group combined treatments group (G). Pia mater (dashed black arrow); Dura mater (black arrow); B: Bone; S: spinal cord H&E, X: 40 bar 200 μm

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BMC Neuroscience

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