NPT100-18A rescues mitochondrial oxidative stress and neuronal degeneration in human iPSC-based Parkinson’s model

BMC Neuroscience

Table 1 Probands and iPSC lines

Proband	Abbreviation cell line	iPSC line name	Gender	Ethnicity	Age at biopsy (y)	Diagnosis	Genotype	Reference
P1	P1.1	CSC1-A	Female	Caucasian	53	Early-onset PD	Monoallelic SNCA locus duplication	[31, 35, 36]
P1	P1.2	CSC1-D	Female	Caucasian
P2	P2.1	SDi1-R-C3	Female	Caucasian	58	Early-onset PD	Monoallelic SNCA locus duplication	[23, 35, 36, 53]
P2	P2.2	SDi1-R-C11	Female	Caucasian
C1	C1	UKERi82A-S1_017	Female	Caucasian	66	Unaffected control	SNCA wildtype	[36]
C2	C2	UKERi33Q-R1-06	Female	Caucasian	45	Unaffected control	SNCA wildtype	[23, 31, 36, 53]
C3	C3.1	UKERiO3H-R1-001	Male	Caucasian	71	Unaffected control	SNCA wildtype	[23, 31, 36, 53, 54]
C3	C3.2	UKERiO3H-R1-005	Male	Caucasian

ISSN: 1471-2202