Table 2 Subgroup analysis of DFS
From: Association between apolipoprotein E ε4 status and the risk of Alzheimer’s disease: a meta-analysis
Endpoint | Factor | No. of studies | Heterogeneity test (I2, P) | Effect model | HR | 95%CI of HR | Conclusion |
|---|---|---|---|---|---|---|---|
DFS | region | ||||||
Asian | 11 | 92.7,0.000 | random | 2.18 | 1.47,3.22 | significant | |
Europen | 12 | 90.9,0.000 | random | 1.94 | 1.33,2.83 | significant | |
USA | 7 | 75.4, 0.000 | random | 2.00 | 1.40, 2.88 | significant | |
study design | |||||||
P | 22 | 94.3,0.000 | random | 2.02 | 1.46,2.78 | significant | |
R | 8 | 83.1,0.000 | random | 2.13 | 1.54,2.93 | significant | |
Cutoff method | |||||||
ROC | 4 | 0.0,0.661 | fixed | 3.07 | 2.26,4.16 | significant | |
Others | 26 | 93.9,0.000 | random | 1.95 | 1.49,2.54 | significant |