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Fig. 6 | BMC Neuroscience

Fig. 6

From: Dorsal root ganglion inflammation by oxaliplatin toxicity: DPEP1 as possible target for peripheral neuropathy prevention

Fig. 6

Immunostaining for DPEP1-C and GFAP. Controls: yellow arrowheads point to GFAP signal (red), around neurons, apparently in cytosol of glia cell, colocalizing with DPEP1-C specific fluorescence (green) in cytosol and in the periphery of nuclei. White arrowheads point to DPEP1-C positive and GFAP negative tubular structures (axons); magenta arrowheads point to presumably activated Schwann cells. Yellow star is inside a blood vessel. OxPt treated rats: white arrows point to GFAP positive cells. Mesh pattern of DPEP1-C fluorescence in some neurons (red arrowheads). Yellow arrowheads point DPEP1-C cells in tubular structures (axons of root). Zeiss LSM980 Airyscan-2 confocal microscope. Bar = 40 μm

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