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Fig. 5 | BMC Neuroscience

Fig. 5

From: Dorsal root ganglion inflammation by oxaliplatin toxicity: DPEP1 as possible target for peripheral neuropathy prevention

Fig. 5

Co-immunostaining for DPEP1 (green) and IL-6 (red) in control and OxPt-treated rat DRG. Control: IL-6 positive (red) in few endothelial cells of control panels (white arrows) and faint or no signal in neurons and in glia cells in (yellow stars). DRG from OxPt-treated rat: shows low intensity for IL-6 in the periphery of neurons and glia cells (yellow arrowheads) and in axons of root, either in longitudinal (white arrows) or transversal sections (white arrowheads). DPEP1-C and IL-6 fluorescence signals colocalize (DPEP1-C and IL-6 panels, due to difference in intensity signals this fact is barely shown in merges). Zeiss LSM980 Airyscan-2 confocal microscope. Bar = 40 μm

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BMC Neuroscience

ISSN: 1471-2202

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