Fig. 6

Analysis of GDNF and GFRα1 protein expression in the hippocampus of F1 mice. A: cropped representative immunoreactive bands for GDNF and GFRα1 in the hippocampi of F1 mice aged 3 months (3 M) and 15 months (15 M). B, C: quantification of GDNF (B) and GFRα1 (C) protein levels in CON mice. D, E: Quantification of GDNF and GFRα1 protein levels across treatments and ages. n = 6 per group. Data are presented as mean ± SEM. * P < 0.05, ** P < 0.01 compared with CON-F. ^#P < 0.05, ^##P < 0.01 compared with CON-M. CON-F female mice exposed to saline in utero, CON-M male mice exposed to saline in utero, LPS-F female mice exposed to inflammation in utero, LPS-M male mice exposed to inflammation in utero