Fig. 3

Time-dependent alterations in hippocampal responses to perforant path stimulation after a HFS. The effect of AM-251 (CB1 receptor antagonist), CGP (GABAB receptor antagonist), and AM + CGP on LTP induced by high frequency stimulation to performant path. The graphs show the changes of slope (a) and amplitude (b) of fEPSP recorded from DG neurons compared to baseline (control, CTRL). Values are reported as mean ± SEM % of baseline. *P < 0.05, **P < 0.01, ns not significant