Fig. 5

RSFC in high TA subgroup. Resting state functional connectivity (RSFC) between right amygdala and pregenual anterior cingulate cortex (pgACC)/ventro-medial prefrontal cortex (vmPFC) in the above average trait anxiety (TA) subgroup (\(TA \ge \ 35\); n = 17) for placebo (red) and Nx4 (blue) condition. A RSFC increased from pre-stress resting state (RS1) to post-stress resting state (RS2) in placebo condition and decreased from RS1 to RS2 in Nx4 condition. B Stress-induced RSFC change (contrast \(RS2>RS1\)) is reduced in Nx4 versus placebo condition. Data are given as individual dot blots with meanstandard error of mean. Asterisks indicate significant differences (* \(p<0.05\) and ** \(p<0.01\))