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Fig. 1 | BMC Neuroscience

Fig. 1

From: Trait anxiety is related to Nx4’s efficacy on stress-induced changes in amygdala-centered resting state functional connectivity: a placebo-controlled cross-over trial in mildly to moderately stressed healthy volunteers

Fig. 1

Study flow of the NEURIM trial. On each of the two study days, a structural MRI scan and a resting state (RS) measurement were conducted during a simultaneous EEG/fMRI scan session. After administering a single dose (three tablets) of Nx4 or placebo, two computerized tests, the Attention Modulation by Salience Task (AMST) and an auditory oddball task, were performed while EEG data were acquired. A second EEG/fMRI scan session was conducted, starting 40 to 60 minutes after dosing, including an initial RS session (RS1) followed by the Hariri emotional face-matching task, an expectancy task, and the ScanSTRESS paradigm as well as another resting-state session (RS2). This publication focuses on the fMRI data from RS1 (pre-stress) and RS2 (post-stress) marked in green

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BMC Neuroscience

ISSN: 1471-2202

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