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Fig. 1 | BMC Neuroscience

Fig. 1

From: A circular RNA derived from GLIS3 accelerates the proliferation of glioblastoma cells through competitively binding with miR-449c-5p to upregulate CAPG and GLIS3

Fig. 1

GBM cell proliferation and apoptosis are regulated by interfering circGLIS3. A qRT-PCR detected the expression of circGLIS3 in cells transfected with sh-circ or co-transfected with sh-circ + pcDNA3.1-circ. B, C Proliferation of cells transfected with sh-circGLIS3 or co-transfected with sh-circ + pcDNA3.1-circ was analyzed by CCK-8 and EdU assays. D Colony formation assay was implemented to test cell proliferation of U251 and LN229 transfected with sh-circGLIS3 or co-transfected with sh-circ + pcDNA3.1-circ. E The apoptotic rate of U251 and LN229 cells after transfection of sh-circGLIS3 or co-transfection with sh-circ + pcDNA3.1-circ was measured through TUNEL assay. One-way ANOVA was applied for statistical analysis. **P < 0.01

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BMC Neuroscience

ISSN: 1471-2202

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