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Table 2 ABR thresholds in Nav1.9+/+ (WT), +/−, −/− mice at 2 months of age

From: SCN11A gene deletion causes sensorineural hearing loss by impairing the ribbon synapses and auditory nerves

Group

Frequency (kHz)

2

8

12

16

Nav1.9+/+

57.5 ± 9.9

39.0 ± 8.1

41.0 ± 11.4**

41.7 ± 6.6***

Nav1.9+/−

70.0 ± 7.1

42.5 ± 15.5

42.5 ± 15.0**

58.8 ± 14.9*

Nav1.9−/−

70.0 ± 11.5

36.7 ± 6.6

79.3 ± 13.7

78.9 ± 10.5

  1. Asterisks indicate significant differences (*p < 0.05, **p < 0.01, ***p < 0.001) as compared with the Nav1.9−/− group
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BMC Neuroscience

ISSN: 1471-2202

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