Figure 13
Locomotor activity in a novel environment and body mass AcbC-lesioned rats were significantly hyperactive compared to sham-operated controls, and gained less weight, in both Experiments 1 & 2. (a) Locomotor activity in Experiment 1. Analysis using the model lesion2 × (bin12 × S) revealed effects of lesion (F
1,42 = 5.12, * p = .029), reflecting hyperactivity in the AcbC group, with additional effects of bin (F
5.7,237.9 = 13.3, 
= .515, p < .001), reflecting habituation, and a lesion × bin interaction (F
5.7,237.9 = 2.52, = .515, # p = .024). (b) Locomotor activity in Experiment 2. The same patterns were observed (data from five subjects were not recorded due to a mechanical error; lesion: F
1,37 = 9.155, ** p = .004; bin: F
9.3,345.2 = 13.5, = .848, p < .001; lesion × bin: F
9.3,345.2 = 3.18, = .848, ## p = .001). (c) Preoperative and final body mass in both experiments. Preoperatively, masses did not differ between groups (Experiment 1: F < 1, NS; Experiment 2: F
1,42 = 1.008, NS), but in both cases, AcbC-lesioned subjects gained less mass than controls (Experiment 1: lesion × time: F
1,41 = 95.9, ### p < .001; group difference at second time point: F
1,42 = 88.4, *** p < .001; Experiment 2: lesion × time: F
1,42 = 13.53, ## p = .001; group difference at second time point: F
1,42 = 7.37, ** p = .01).