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Figure 2 | BMC Neuroscience

Figure 2

From: Epidermal growth factor (EGF) withdrawal masks gene expression differences in the study of pituitary adenylate cyclase-activating polypeptide (PACAP) activation of primary neural stem cell proliferation

Figure 2

B-value distributions for each comparison. The x-axis shows the M-value (log2(Cy5/Cy3)) for each gene and the y-axis the corresponding B-value (calculated by an empirical Bayes moderated t-test).The B-value scores the genes according to their probability of differential expression. Higher B-value means higher probability of differential expression. Dotted lines are drawn at M-values 0.6 and -0.6, i.e. at a 1.5-fold difference in signal intensity between the compared samples, and at B = 9.3, corresponding to a Holm adjusted p-value of 0.0001. These values correspond to the thresholds set for differential expression in this study.

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