Figure 4

Darkfield photomicrographs of 6 μm thick L4 DRG sections processed for in situ hybridization with probes indicated. GTPcyclo, IES-JE, CCHL2A and VGF transcripts show a strong upregulation following injury compared to the naïve. SNAP25, and 5HT3 receptor mRNA show a downregulation following injury to the peripheral neurons. Scale bar = 200 μm.